Drug Profile


Alternative Names: Debio 0614; PST 2744; ST 2744

Latest Information Update: 15 Sep 2017

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At a glance

  • Originator sigma-tau SpA
  • Developer CVie Therapeutics
  • Class Amines; Androstanols; Cardiotonics; Heart failure therapies; Ketosteroids; Oximes; Small molecules
  • Mechanism of Action Adenosine triphosphatase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Decompensated heart failure

Most Recent Events

  • 05 Aug 2016 CVie Therapeutics and ScinoPharm agree to co-develop istaroxime in Taiwan for Chronic heart failure
  • 17 Aug 2015 Phase-II development is ongoing in Italy
  • 31 Mar 2015 Phase-II clinical trials in Decompensated heart failure (In adults, In the elderly) in China (IV)
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