Drug Profile


Alternative Names: Abetafen; Modrastane; Modrefen; Modrenal

Latest Information Update: 14 Dec 2016

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At a glance

  • Originator Stegram Pharmaceuticals
  • Class Androstanols; Testosterone congeners
  • Mechanism of Action 3-hydroxysteroid dehydrogenase inhibitors; Estrogen receptor antagonists; Signal transduction pathway inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Breast cancer
  • No development reported Adrenal cortical hyperfunction; Prostate cancer
  • Discontinued Alzheimer's disease

Most Recent Events

  • 08 Apr 2011 Genzyme Corporation has been acquired by sanofi-aventis
  • 08 Sep 2009 No development reported - Clinical for Breast cancer in European Union (PO)
  • 08 Sep 2009 No development reported - Clinical-Phase-Unknown for Breast cancer in Australia (PO)
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