Pelareorep

Drug Profile

Pelareorep

Alternative Names: PO-BB0209; REOLYSIN; Reovirus; Reovirus - Oncolytics Biotech; Reovirus anticancer; Reovirus antitumour; Reovirus Serotype 3 - Dearing Strain; Respiratory Enteric Orphan virus; Wild-type reovirus

Latest Information Update: 19 Sep 2017

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At a glance

  • Originator Oncolytics Biotech
  • Developer Mayo Clinic; National Cancer Institute (Canada); National Cancer Institute (USA); Oncolytics Biotech; University of Leeds; University of Southern California
  • Class Antineoplastics; Oncolytic viruses
  • Mechanism of Action Apoptosis stimulants; Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Glioma; Peritoneal cancer; Ovarian cancer; Gastric cancer; Pancreatic cancer; Fallopian tube cancer
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Head and neck cancer
  • Phase II Brain cancer; Breast cancer; Colorectal cancer; Lung cancer; Malignant melanoma; Non-small cell lung cancer; Ovarian cancer; Pancreatic cancer; Prostate cancer; Sarcoma
  • Phase I/II Glioma
  • Phase I Multiple myeloma; Solid tumours
  • Preclinical Hepatocellular carcinoma; Viral hepatitis

Most Recent Events

  • 18 Sep 2017 Oncolytics Biotech announces intention to submit BLA to US FDA for Breast Cancer
  • 16 Sep 2017 University of Leeds plans a phase I/II trial for Malignant melanoma(Monotherapy, Combination therapy, Late-stage disease)(NCT03282188)
  • 11 Sep 2017 Updated efficacy data from the phase II IND 213 trial in Breast cancer preseanted at the European Society for Medical Oncology Congress (ESMO-2017)
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