Drug Profile


Alternative Names: CX 691; ORG 24448

Latest Information Update: 18 Dec 2008

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At a glance

  • Originator Cortex Pharmaceuticals; University of California at Irvine
  • Developer Organon
  • Class Antidepressants; Antipsychotics; Neuroprotectants; Nootropics; Oxadiazoles; Piperidines; Small molecules
  • Mechanism of Action AMPA receptor agonists; Glutamate agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Major depressive disorder; Schizophrenia

Most Recent Events

  • 19 Nov 2007 Organon has been acquired by Schering-Plough
  • 17 Oct 2007 Final efficacy data from a clinical trial in healthy elderly volunteers presented at the 20th Annual Congress of the European College of Neuropsychopharmacology (ECNP-2007)
  • 17 Jan 2001 Phase-I clinical trials for Psychotic disorders in USA (PO)
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