Drug Profile


Alternative Names: trans-ISA 247; trans-R 1524; ISA(TX)247; ISA-247; ISAtx 247; ISATx247; Orelvo; R-1524; Voclera

Latest Information Update: 23 May 2017

Price : $50

At a glance

  • Originator Isotechnika
  • Developer Atrium Medical Corporation; Aurinia Pharmaceuticals; Isotechnika; Paladin Labs
  • Class Antipsoriatics; Ciclosporins; Eye disorder therapies; Skin disorder therapies
  • Mechanism of Action Calcineurin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Lupus nephritis
  • No development reported Renal transplant rejection
  • Discontinued Coronary artery restenosis; Plaque psoriasis; Rheumatoid arthritis

Most Recent Events

  • 17 May 2017 Phase-III clinical trials in Lupus nephritis in USA (PO) (NCT03021499)
  • 28 Apr 2017 Phase-III clinical trials in Lupus nephritis in Spain, Bulgaria (PO) (EudraCT2016-004045-81)
  • 06 Apr 2017 Aurinia Pharmaceuticals completes the phase II AURA-LV trial in Lupus nephritis (Adjunctive treatment) in USA, Bangladesh, Belarus, Bulgaria, China, Ecuador, Guatemala, Georgia, South Korea, Mexico, Philippines, Poland, Russia, Serbia, Singapore, Spain, Sri Lanka, Taiwan, Thailand and Ukraine (PO)
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