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Nimotuzumab - InnoMab

Drug Profile

Nimotuzumab - InnoMab

Alternative Names: BIOMAb EGFR; CIMAher; Cimaher; DE-766; h-R3; KI-0501; KI-0502; OSAG101; Taixinsheng; TheraCIM; TheraCIM hR3; Theraloc; VECTHIX

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator Center of Molecular Immunology; CIMYM
  • Developer Biocon Biopharmaceuticals; Biotech Pharmaceutical; Center of Molecular Immunology; CIMYM; Daiichi Sankyo Inc; Eurofarma; Gilead Sciences; Innogene Kalbiotech; InnoMab; Kuhnil Pharmaceutical Company; Laboratorios Pisa; Oncoscience
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Epidermal growth factor receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Glioma; Pancreatic cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Anaplastic astrocytoma; Brain cancer; Glioblastoma; Glioma; Head and neck cancer; Nasopharyngeal cancer; Oesophageal cancer
  • Phase III Cervical cancer; Non-small cell lung cancer; Pancreatic cancer
  • Phase II/III Triple negative breast cancer
  • Phase II Colorectal cancer
  • No development reported Breast cancer; Gastric cancer; Polycystic kidney disease; Prostate cancer
  • Discontinued Brain metastases; Squamous cell cancer

Most Recent Events

  • 03 Aug 2023 Biotech Pharmaceutical plans a phase III NOTABLE-307 trial in Gastric cancer (Recurrent, Second-line therapy or greater, Metastatic disease, Combination therapy) in September 2023 (IV) (NCT05978050)
  • 03 Jun 2022 Efficacy and adverse events data from a phase III trial in Pancreatic cancer were presented at the 58th Annual Meeting of the American Society of Clinical Oncology (ASCO-2022)
  • 03 Jun 2022 Safety and efficacy data from a phase III trial in Nasopharyngeal cancer presented at the 58th Annual Meeting of the American Society of Clinical Oncology (ASCO-2022)
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