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Drug Profile

Pyridoxamine - Kowa

Alternative Names: BST-4001; K-163; K163SZ; Pyridorin; Pyridoxamine dihydrochloride; Pyridoxamine hydrochloride

Latest Information Update: 21 Oct 2021

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At a glance

  • Originator BioStratum
  • Developer Kowa; NephroGenex
  • Class Antipsychotics; Methylamines; Picolines; Pyridines; Small molecules
  • Mechanism of Action Advanced glycosylation end product inhibitors; Oxygen radical scavengers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No
  • Available For Licensing Yes - Diabetic nephropathies

Highest Development Phases

  • Phase II Schizophrenia
  • No development reported Acute kidney injury
  • Discontinued Diabetic nephropathies

Most Recent Events

  • 14 Apr 2021 Pyridoxamine is still in phase II trials for Schizophrenia in Japan (JapicCTI-173780) (Kowa pipeline, April 2021)
  • 14 Apr 2021 Discontinued - Phase-III for Diabetic nephropathies in Spain, USA, Puerto Rico, Poland, Mauritius, France, Israel, Hong Kong, Germany, Hungary, Australia, Bulgaria (PO)
  • 28 Jun 2018 No recent reports of development identified for preclinical development in Acute kidney injury in USA (IV)

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