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Alitretinoin oral - Ligand Pharmaceuticals

Drug Profile

Alitretinoin oral - Ligand Pharmaceuticals

Alternative Names: 9-cis Retinoic acid - oral; ALRT - oral; LG 1057 - oral; LGD 1057 - oral; LGN 1057 - oral

Latest Information Update: 24 Oct 2021

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At a glance

  • Originator Ligand Pharmaceuticals
  • Class Antineoplastics; Keratolytics; Retinoids; Skin disorder therapies; Small molecules
  • Mechanism of Action Protein synthesis inhibitors; Retinoic acid receptor agonists; Retinoic acid receptor antagonists; Retinoid X receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Acute promyelocytic leukaemia
  • New Molecular Entity No

Highest Development Phases

  • Discontinued Acute promyelocytic leukaemia; Cancer; Head and neck cancer; Kaposi's sarcoma; Lung cancer; Multiple myeloma; Non-Hodgkin's lymphoma; Ovarian cancer; Preleukaemia; Prostate cancer; Psoriasis; Renal cancer; Retinal disorders

Most Recent Events

  • 11 Sep 2003 No development reported - Phase-II for Cancer in European Union (PO)
  • 11 Sep 2003 No development reported - Phase-II for Head and neck cancer in USA (PO)
  • 11 Sep 2003 No development reported - Phase-II for Ovarian cancer in USA (PO)
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