AR 67

Drug Profile

AR 67

Alternative Names: (20S)-7-t-Butyldimethylsilyl-10-hydroxycamptothecin; AR-67; D 67; DB-67

Latest Information Update: 21 Nov 2016

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At a glance

  • Originator University of Pittsburgh
  • Developer Arno Therapeutics; TaiGen Biotechnology; TTY Biopharm
  • Class Antineoplastics; Camptothecins; Organosilicon compounds
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Discontinued Glioblastoma; Myelodysplastic syndromes; Solid tumours

Most Recent Events

  • 30 Sep 2016 Vivacitas Oncology acquires AR 67 from Arno Therapeutics
  • 18 May 2012 Arno Therapeutics terminates its licence for AR 67 (Arno Therapeutics Form-10K report May 2012)
  • 01 May 2012 Discontinued - Phase-I for Solid tumours in USA (IV)
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