Drug Profile


Alternative Names: Chrysalin; Rusalatide acetate; Thrombin receptor activating peptide; TP 508; TRAP-508

Latest Information Update: 04 Nov 2017

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At a glance

  • Originator University of Texas Medical Branch
  • Developer Baylor College of Medicine; Capstone Therapeutics; Chrysalis BioTherapeutics; Quintiles; University of Texas Medical Branch
  • Class Peptides; Vascular disorder therapies
  • Mechanism of Action Angiogenesis inducing agents; Apoptosis inhibitors; Apoptosis stimulants; Cytokine modulators; Intercellular signalling peptide and protein stimulants; Nitric oxide stimulants; Osteogenesis stimulants; Signal transduction pathway modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Radiation injuries
  • Discontinued Chronic wounds; Diabetic foot ulcer; Fracture; Joint disorders; Myocardial infarction; Periodontal disorders; Spinal disorders; Vascular disorders

Most Recent Events

  • 04 Nov 2017 No recent reports of development identified for preclinical development in Radiation-injuries in USA (Parenteral)
  • 23 Sep 2013 Rusalatide licensed to Chrysalis BioTherapeutics worldwide
  • 23 Sep 2013 Chrysalis BioTherapeutics receives grant from National Cancer Institute for Rusalatide development in Radiation injuries
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