Ticagrelor - AstraZeneca

Drug Profile

Ticagrelor - AstraZeneca

Alternative Names: AR-C-126532; AZD-6140; Brilinta; Brilique

Latest Information Update: 06 Oct 2017

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At a glance

  • Originator AstraZeneca
  • Developer AstraZeneca; The Medicines Company; Uppsala University; Vanderbilt University
  • Class Antithrombotics; Cyclopropanes; Fluorobenzenes; Purine nucleosides; Ribonucleosides; Small molecules
  • Mechanism of Action Platelet ADP receptor antagonists; Purinoceptor P2Y12 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Acute coronary syndromes
  • Phase III Cardiovascular disorders; Stroke
  • Phase II Abdominal aortic aneurysm; Community-acquired pneumonia; Coronary artery disease; Sickle cell anaemia
  • Discontinued Peripheral arterial disorders

Most Recent Events

  • 30 Aug 2017 Pharmacokinetics data from phase I clinical trials in Healthy volunteers presented at the Annual Congress of the European Society of Cardiology (ESC-Card-2017)
  • 26 Aug 2017 Adverse events data from the phase III EUCLID trial in Peripheral artery disease presented at the ESC Congress 2017: Annual Congress of the European Society of Cardiology (ESC-Card-2017)
  • 26 Aug 2017 Updated efficacy data from the phase III EUCLID trial in Peripheral artery disease presented at the ESC Congress 2017: Annual Congress of the European Society of Cardiology (ESC-Card-2017)
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