Ticagrelor - AstraZeneca

Drug Profile

Ticagrelor - AstraZeneca

Alternative Names: AR-C-126532; AZD-6140; Brilinta; Brilique

Latest Information Update: 17 Nov 2017

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At a glance

  • Originator AstraZeneca
  • Developer AstraZeneca; The Medicines Company; Uppsala University; Vanderbilt University
  • Class Antithrombotics; Cyclopropanes; Fluorobenzenes; Purine nucleosides; Ribonucleosides; Small molecules
  • Mechanism of Action Platelet ADP receptor antagonists; Purinoceptor P2Y12 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Acute coronary syndromes
  • Phase III Cardiovascular disorders; Stroke
  • Phase II Abdominal aortic aneurysm; Community-acquired pneumonia; Coronary artery disease; Sickle cell anaemia
  • Discontinued Peripheral arterial disorders

Most Recent Events

  • 28 Nov 2017 AstraZeneca plans the phase III THALES trial for Stroke in Argentina, Australia, Belgium, Brazil, China, Czechia, German, Hong Kong, Hungary, India, Mexico, Peru, Romania, Russia, Saudi Arabia, Slovakia, Spain, Sweden, Thailand, Ukraine and Vietnam , (NCT03354429)
  • 08 Nov 2017 AstraZeneca completes a phase II trial in Abdominal aortic aneurysm in Sweden (PO) (NCT02070653)
  • 30 Aug 2017 Pharmacokinetics data from phase I clinical trials in Healthy volunteers presented at the Annual Congress of the European Society of Cardiology (ESC-Card-2017)
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