Valproate semisodium

Drug Profile

Valproate semisodium

Alternative Names: Depakote; Depakote ER; Divalproex; Divalproex sodium; Divalproex sodium DR 500mg tablets - Abbott Laboratories; Epival; Epival ER

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Abbott Laboratories
  • Class Antiepileptic drugs; Antimanics; Antimigraines
  • Mechanism of Action GABA uptake inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Bipolar disorders; Epilepsy; Migraine
  • Phase III Dementia

Most Recent Events

  • 25 Apr 2017 Abbott terminated a phase III trial in Dementia (In adults, In the elderly) as the investigator closed study and left VAMC in USA (NCT00315900)
  • 15 Mar 2016 Biomarkers information updated
  • 02 Jan 2013 Abbott separates its pharmaceuticals business to a new company named AbbVie
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