Paclitaxel tocopheryl-based emulsion - Sorrento Therapeutics

Drug Profile

Paclitaxel tocopheryl-based emulsion - Sorrento Therapeutics

Alternative Names: IG 004; IG-002; paclitaxel TPGS-based emulsion; QW 8184; S 8184; Tocosol paclitaxel

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Sonus Pharmaceuticals
  • Developer Sorrento Therapeutics
  • Class Antineoplastics; Diterpenes; Paclitaxels; Small molecules; Taxanes
  • Mechanism of Action Tubulin modulators; Tubulin polymerisation promoters
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Discontinued Bladder cancer; Breast cancer; Colorectal cancer; Non-small cell lung cancer; Ovarian cancer; Solid tumours

Most Recent Events

  • 23 Nov 2016 Discontinued - Preclinical for Solid tumours (New delivery system) in USA (IV) (Sorrento Therapeutics pipeline, November 2016)
  • 08 Apr 2014 Further analyses of adverse events data from a phase III trial in Breast cancer presented at the 105th Annual Meeting of the American Association for Cancer Research (AACR-2014)
  • 31 Dec 2013 Preclinical trials in Solid tumours (TPGS-based nanoparticle emulsion) in USA (IV)
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