Drug Profile


Alternative Names: Halofuginone hydrobromide; HT-100; Stenorol™; Tempostatin™

Latest Information Update: 30 Aug 2016

Price : $50

At a glance

  • Originator Collgard Biopharmaceuticals
  • Developer Akashi Therapeutics; Collgard Biopharmaceuticals
  • Class Antifibrotics; Piperidines; Quinazolinones; Small molecules
  • Mechanism of Action Angiogenesis inhibitors; Collagen type I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Duchenne muscular dystrophy; Scleroderma
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Duchenne muscular dystrophy
  • Discontinued Bladder cancer; Cancer; Coronary artery restenosis; Hepatic fibrosis; Kidney disorders; Renal fibrosis; Scleroderma

Most Recent Events

  • 22 Mar 2017 Akashi Therapeutics plans the HALO-DMD-04 trial for Duchenne muscular dystrophy in 2017
  • 15 Dec 2016 Biomarkers information updated
  • 30 Aug 2016 Phase-II development in Duchenne muscular dystrophy is ongoing in USA (PO)
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