Drug Profile


Alternative Names: CF-102; Cl-IB-MECA

Latest Information Update: 11 May 2017

Price : $50

At a glance

  • Originator National Institutes of Health (USA)
  • Developer Can-Fite BioPharma; Rabin Medical Center; Temple University School of Medicine
  • Class Amides; Anti-inflammatories; Antineoplastics; Antivirals; Iodobenzenes; Purine nucleosides; Small molecules
  • Mechanism of Action Adenosine A3 receptor agonists; Hepatitis C virus NS 5 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Hepatocellular carcinoma
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Hepatocellular carcinoma; Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis
  • Preclinical Colorectal cancer; Malignant melanoma; Prostate cancer; Reperfusion injury
  • Discontinued Hepatitis B; Hepatitis C

Most Recent Events

  • 03 May 2017 Phase-II clinical trials in Non-alcoholic fatty liver disease in Israel (PO)
  • 03 May 2017 Phase-II clinical trials in Non-alcoholic steatohepatitis in Israel (PO)
  • 28 Feb 2017 Can-Fite BioPharma plans a phase II trial for Non-alcoholic fatty liver diease in Israel (NCT02927314)
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