Drug Profile


Alternative Names: 2'-deoxy-L-thymidine; B-L-thymidine; Beta-L-thymidine; Epavudine; L-dT; LDT-600; NV-02B; Sebivo; Tyzeka

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Centre National de la Recherche Scientifique; Idenix Pharmaceuticals; University of Montpellier II
  • Developer Novartis
  • Class Antivirals; Nucleosides; Pyrimidines; Small molecules
  • Mechanism of Action DNA-directed DNA polymerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Hepatitis B

Most Recent Events

  • 20 Jul 2017 Telbivudine is still in phase III trials for Hepatitis B (In children, In adolescents) in Ukraine, Romania, South Korea, Israel, Bulgaria, Greece, Turkey and United Kingdom (PO) (NCT02058108)
  • 15 Mar 2016 Biomarkers information updated
  • 16 Jun 2015 Launched for Hepatitis B in Croatia, Finland, Georgia, Latvia, Lithuania, Romania, Oman, Serbia, Armenia, Singapore, Slovakia, Slovenia, South Africa, Taiwan, Venezuela, Estonia, Malta, Hungary, Bahrain, Saudi Arabia, Qatar, Jordan, Nigeria, Sri Lanka, India and Bangladesh (PO) before June 2015
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