Drug Profile


Alternative Names: Azaepothilone B; BMS-247550; Epothilone B analogue; Ixempra; Patupilone analogue

Latest Information Update: 25 Mar 2017

Price : $50

At a glance

  • Originator GBF
  • Developer Bristol-Myers Squibb
  • Class Antineoplastics; Epothilones; Macrolides; Small molecules
  • Mechanism of Action Cell cycle inhibitors; Tubulin polymerisation promoters
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Breast cancer
  • No development reported Gastric cancer; Non-small cell lung cancer; Oesophageal cancer; Pancreatic cancer
  • Discontinued Cancer; Endometrial cancer; Prostate cancer

Most Recent Events

  • 17 Aug 2015 R-Pharm acquires ixabepilone from Bristol-Myers Squibb
  • 05 May 2015 Phase-II development for Breast cancer (Early-stage disease, Adjuvant therapy) is ongoing in Argentina, Asia, European Union, India, Peru, Philippines, Russia, South Korea and USA
  • 05 May 2015 Phase-III development for Breast cancer (Early-stage disease, Adjuvant therapy) is ongoing in USA and Puerto Rico
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