Research programme: protein kinase inhibitors - Novartis/Vertex

Drug Profile

Research programme: protein kinase inhibitors - Novartis/Vertex

Alternative Names: VX-322; VX-398; VX-608

Latest Information Update: 24 Mar 2011

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At a glance

  • Originator Vertex Pharmaceuticals
  • Developer Novartis; Vertex Pharmaceuticals
  • Class Small molecules
  • Mechanism of Action Fms-like tyrosine kinase 3 inhibitors; Protein kinase inhibitors; Protein tyrosine kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Cancer; Cardiovascular disorders; Inflammation; Neurological disorders

Most Recent Events

  • 17 Nov 2004 Novartis has selected VX 322 for clinical development
  • 10 Feb 2004 Vertex and Novartis amend research agreement
  • 26 May 2000 Preclinical development for Cardiovascular disorders in USA (Unknown route)
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