Drug Profile


Alternative Names: R 450; RO 115-1240

Latest Information Update: 19 May 2004

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At a glance

  • Originator Roche
  • Developer Chugai Pharmaceutical
  • Class Antispasmodics; Imidazoles; Small molecules; Sulfonamides
  • Mechanism of Action Alpha 1 adrenergic receptor agonists; G protein-coupled receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Stress incontinence

Most Recent Events

  • 30 Apr 2004 Discontinued - Phase-I for Stress incontinence in Japan (PO)
  • 30 Apr 2004 Discontinued - Phase-II for Stress incontinence in Europe (PO)
  • 05 Feb 2004 A study has been added to the adverse events and Genitourinary Disorders therapeutic trials sections
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