Drug Profile


Alternative Names: GC-1111 - Sanofi Genzyme; HGT-2310; I2S; idursulfase-IT; SHP-609

Latest Information Update: 04 Jan 2017

Price : $50

At a glance

  • Originator Shire Pharmaceuticals Group
  • Developer Sanofi Genzyme; Shire
  • Class Iduronate sulfatases
  • Mechanism of Action Iduronate sulfatase replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Mucopolysaccharidosis II
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Mucopolysaccharidosis II

Most Recent Events

  • 30 Sep 2016 Shire completes enrolment in a phase III trial in Mucopolysaccharidosis II (Hunter's syndrome) in Spain, USA, Argentina, Mexico, United Kingdom, Australia, Canada and Colombia
  • 05 Jan 2016 Shire plans a phase II/III trial for Hunter syndrome (Intrathecal)
  • 28 May 2015 Shire initiates enrolment in a phase II/III extension study for Mucopolysaccharidosis II in USA, Canada, Colombia, Mexico, Spain and United Kingdom (NCT02412787)
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