Research programme: bacterial DNA gyrase inhibitors - Vertex

Drug Profile

Research programme: bacterial DNA gyrase inhibitors - Vertex

Alternative Names: VRT-125853; VRT-752586; VX-692; VX-883; VXc-486/VXc-100

Latest Information Update: 04 Nov 2017

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At a glance

  • Originator Vertex Pharmaceuticals
  • Class Benzimidazoles
  • Mechanism of Action DNA gyrase inhibitors; DNA topoisomerase IV inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Bacterial infections

Most Recent Events

  • 04 Nov 2017 No recent reports of development identified for preclinical development in Bacterial-infections in USA
  • 25 May 2016 Spero Therapeutics acquires VXc 486/VXc 100 from Vertex Pharmaceuticals
  • 17 Feb 2009 Preclinical development is ongoing in USA
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