Drug Profile


Alternative Names: BCX-1777; Fodosine; Forodesine hydrochloride; Immucillin-H

Latest Information Update: 25 May 2016

Price : $50

At a glance

  • Originator Albert Einstein College of Medicine; Industrial Research Limited
  • Developer BioCryst Pharmaceuticals; Mundipharma International
  • Class Antineoplastics; Antipsoriatics; Purine nucleosides; Pyrimidinones; Small molecules
  • Mechanism of Action Immunosuppressants; Purine nucleoside phosphorylase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Chronic lymphocytic leukaemia; Hairy cell leukaemia; Cutaneous T cell lymphoma; Leukaemia; Acute lymphoblastic leukaemia; T cell prolymphocytic leukaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Peripheral T-cell lymphoma
  • Phase I Haematological malignancies
  • No development reported Chronic lymphocytic leukaemia; Cutaneous T cell lymphoma

Most Recent Events

  • 26 Feb 2016 Mundipharma announces intention to submit NDA to the Japanese Ministry of Health, Labor and Welfare (BioCryst Pharmaceutical, Form 10-K, February 2016)
  • 26 Feb 2016 Mundipharma completes a phase II trial in Peripheral T-cell lymphoma in Japan (BioCryst Pharmaceutical, Form 10-K, February 2016)
  • 03 Sep 2015 No recent reports of development identified - Phase-II for Chronic lymphocytic leukaemia (Second-line therapy or greater) in USA and Australia (PO)
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