Drug Profile


Alternative Names: CBD4124; CDB-4124; Proellex; Proellex®-V; Progenta; Telapristone acetate

Latest Information Update: 12 Apr 2017

Price : $50

At a glance

  • Originator National Institute of Child Health and Human Development
  • Developer Northwestern University Feinberg School of Medicine; Repros Therapeutics
  • Class Antiprogestogens; Norpregnadienes; Small molecules
  • Mechanism of Action Selective progesterone receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Breast cancer; Endometriosis; Uterine leiomyoma
  • Suspended Anaemia

Most Recent Events

  • 10 Apr 2017 Repros Therapeutic meets the US FDA in a Type C/ Guidance meeting for the development of oral telapristone for the treatment of Uterine fibroids
  • 19 Dec 2016 Updated efficacy data from the phase II ZPE-201 trial in Endometriosis released by Repros Therapeutics
  • 19 Dec 2016 Repros Therapeutics plans a phase III trial for Endometriosis in USA
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