Peginterferon alfa-2b + ribavirin

Drug Profile

Peginterferon alfa-2b + ribavirin

Alternative Names: Cotronak + peginterferon alfa-2b; PEG interferon-alpha-2b + ribavirin; PEG-Intron + REBETOL; PEG-Rebetron; Pegetron; Pegylated interferon-alpha-2b + ribavirin; Ribavirin + peginterferon alfa-2b; SCH-54031 + SCH-18908

Latest Information Update: 14 Aug 2015

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At a glance

  • Originator Schering-Plough
  • Developer Merck & Co
  • Class Antivirals; Interferons; Nucleosides
  • Mechanism of Action Enzyme inhibitors; Immunostimulants; Interferon alpha stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Marketed Hepatitis C

Most Recent Events

  • 09 Apr 2015 Merck Sharp & Dohme terminates phase III trial in Hepatitis C (in type C compensated liver cirrhosis patients) in Japan (NCT00811967)
  • 17 Jul 2013 The UK's National Institute for Health and Care Excellence issues draft guidance recommending peginterferon alfa-2b in combination with ribavirin for Hepatitis C (in children, in adolescents)
  • 12 Oct 2011 CTP 36510 NCT00724893; not added as trial is prospective and is being conducted in Canada (already launched here)
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