Research programme: BACE1 protein inhibitors - Astellas Pharma/CoMentis

Drug Profile

Research programme: BACE1 protein inhibitors - Astellas Pharma/CoMentis

Alternative Names: BACE inhibitors - CoMentis; Disease modifying Alzheimer's disease therapy - CoMentis; OM 991; OM 992

Latest Information Update: 04 Nov 2017

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At a glance

  • Originator CoMentis
  • Class Small molecules
  • Mechanism of Action BACE1 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No

Highest Development Phases

  • No development reported Alzheimer's disease

Most Recent Events

  • 04 Nov 2017 No recent reports of development identified for preclinical development in Alzheimer's-disease in USA (PO)
  • 16 Oct 2014 Astellas Pharma exercises option to terminate its collaboration agreement with CoMentis
  • 25 Apr 2008 Astellas Pharma and CoMentis have entered into an exclusive worldwide collaboration agreement to develop and commercialise products from CoMentis' β-secretase inhibitor programme
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