Drug Profile


Alternative Names: 177Lu-J591; 90Y-J591; Anti-PSMA monoclonal antibody J591; huJ 591; J 591; Lu-177-J591; Lutetium-177-labelled anti-PSMA monoclonal antibody J591; MLN 591RL; MLN591; Monoclonal antibody J591; muJ591; Radiolabelled J591; Radiolabelled MLN591

Latest Information Update: 23 Jan 2017

Price : $50

At a glance

  • Originator Cornell University
  • Developer BZL Biologics; Weill Cornell Medical College
  • Class Antineoplastics; Drug conjugates; Immunotoxins; Monoclonal antibodies; Radiopharmaceuticals
  • Mechanism of Action Ionising radiation emitters
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Prostate cancer
  • Phase I Solid tumours

Most Recent Events

  • 18 Jan 2017 Telix Pharmaceuticals and Atlab Pharma agree to co-develop ATL 101 for Prostate cancer
  • 18 Jan 2017 Atlab Pharma and Telix Pharmaceuticals plan a phase IIb trial for in Prostate cancer (Metastatic disease)
  • 01 Jan 2016 Phase-I clinical trials in Prostate cancer (Neoadjuvant therapy) in USA (IV) (NCT02693860)
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