Botulinum toxin A - Merz Pharma

Drug Profile

Botulinum toxin A - Merz Pharma

Alternative Names: Botulinum neurotoxin type A free from complexing proteins (NT 201) - Merz Pharmaceuticals; Incobotulinum toxin A; NT-201; Xeomin

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator BIOTECON Therapeutics
  • Developer Merz Pharma; Merz Pharmaceuticals GmbH; Yale University
  • Class Antispasmodics; Bacterial proteins; Bacterial toxins; Botulinum toxins; Muscle relaxants
  • Mechanism of Action Acetylcholine inhibitors; Glutamate-antagonists; Neuromuscular blocking agents
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Marketed Blepharospasm; Dystonia; Glabellar lines; Muscle spasticity; Torticollis
  • Phase III Sialorrhoea
  • Phase II Essential tremor; Trigeminal neuralgia
  • No development reported Pain
  • Discontinued Cancer pain

Most Recent Events

  • 07 Jun 2017 Efficacy and safety data from a phase III trial in Sialorrhoea released by Merz Neurosciences
  • 01 May 2017 Thomas Jefferson University and Merz Pharmaceuticals terminates a phase II trial in Trigeminal neuralgia in USA (IM) (NCT02088632)
  • 22 Apr 2017 Pooled efficacy data from two phase III trials in Muscle spasticity presented at the 69th Annual Meeting of the American Academy of Neurology (AAN-2017)
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