Drug Profile


Latest Information Update: 23 Mar 2012

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At a glance

  • Originator Curis
  • Developer Curis; Johns Hopkins University School of Medicine
  • Class Alkaloids; Antineoplastics; Small molecules
  • Mechanism of Action Hedgehog cell-signalling pathway inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Breast cancer; Cancer

Most Recent Events

  • 08 Sep 2004 Preclinical trials in Breast cancer in Japan (unspecified route)
  • 08 Sep 2004 A preclinical study has been added to the Cancer pharmacodynamics section
  • 11 Sep 2002 Preliminary data from a preclinical study have been added to the pharmacodynamics section
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