Riociguat

Drug Profile

Riociguat

Alternative Names: Adempas; BAY-32521; BAY-63-2521

Latest Information Update: 10 Oct 2017

Price : *
* Final gross price and currency may vary according to local VAT and billing address.

At a glance

  • Originator Bayer
  • Class 2 ring heterocyclic compounds; Carbamates; Fluorobenzenes; Pyrazoles; Pyridines; Pyrimidines; Small molecules; Vascular disorder therapies
  • Mechanism of Action Guanylate cyclase stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Systemic scleroderma; Pulmonary hypertension; Pulmonary arterial hypertension
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Pulmonary arterial hypertension; Pulmonary hypertension
  • Phase II Cystic fibrosis; Raynaud's disease; Systemic scleroderma

Most Recent Events

  • 10 Oct 2017 Bayer terminates phase II trial in Cystic fibrosis in USA, Canada, Germany, the Netherlands, United Kingdom, Belgium, France, Greece and Italy, based on multiple factors, including the design of part 2 is no longer appropriate (NCT02170025)
  • 01 Dec 2016 Bayer completes a phase III trial for Pulmonary Hypertension in the US, Canada, the UK, Belgium, Czech Republic, France, Germany, Italy and Switzerland (NCT02007629)
  • 01 Oct 2016 Bayer completes a phase I trial for pharmacokinetic interaction trial for Pulmonary hypertension (In patients with HIV infections) in USA (NCT02556268)
Restricted Access

Oops, it looks like you don’t have a valid subscription to this content. To gain full access to the content and functionality of the AdisInsight database try one of the following.

  • with a username/password associated to an account with a valid subscription
  • Contact your organization’s admin about adding this content to your AdisInsight subscription
  • Request a trial

If you are a subscriber to this content then contact us at AsktheExpert.AdisInsight@springer.com so we can help.

Back to top