Drug Profile


Alternative Names: ACP-103; BVF-048; Nuplazid; Pimavanserin tartrate

Latest Information Update: 26 Jul 2017

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At a glance

  • Originator ACADIA Pharmaceuticals
  • Class Antiparkinsonians; Antipsychotics; Piperidines; Small molecules
  • Mechanism of Action Serotonin 2A receptor inverse agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Psychotic disorders
  • Phase III Schizophrenia
  • Phase II Agitation; Major depressive disorder
  • Discontinued Drug-induced akathisia; Drug-induced dyskinesia; Insomnia

Most Recent Events

  • 09 May 2017 ACADIA Pharmaceuticals plans a phase III trial for Psychotic disorders (Alzheimer's disease-associated psychosis) in the second half of 2017
  • 21 Mar 2017 ACADIA Pharmaceuticals initiates phase II trial for Agitation in Spain (EudraCT2016-001128-78)
  • 20 Dec 2016 Topline efficacy data from phase II trials in Psychotic disorders (Alzheimer's disease-associated psychosis) released by ACADIA Pharmaceuticals
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