Pimavanserin - ACADIA Pharmaceuticals

Drug Profile

Pimavanserin - ACADIA Pharmaceuticals

Alternative Names: ACP-103; BVF-048; Nuplazid; Pimavanserin tartrate

Latest Information Update: 15 Nov 2017

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At a glance

  • Originator ACADIA Pharmaceuticals
  • Class Antiparkinsonians; Antipsychotics; Piperidines; Small molecules
  • Mechanism of Action Serotonin 2A receptor inverse agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Psychotic disorders
  • Phase III Schizophrenia
  • Phase II Agitation; Major depressive disorder
  • Discontinued Drug-induced akathisia; Drug-induced dyskinesia; Insomnia

Most Recent Events

  • 03 Nov 2017 Efficacy and adverse events data from the phase II Study 019 released by Acadia Pharmaceuticals
  • 05 Oct 2017 Phase-III clinical trials in Schizophrenia (Adjunctive treatment, Treatment-experienced) in Germany (PO) (EudraCT2016-003437-18)
  • 04 Oct 2017 Pimavanserin receives Breakthrough Therapy status for Psychotic disorders (Dementia-associated psychosis) in USA
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