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Ethyl eicosapentaenoic acid - Amarin

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Drug Profile

Ethyl eicosapentaenoic acid - Amarin

Alternative Names: VAZKEPA; AMR-101; Eicosapentaenoic acid ethyl ester - Amarin; Eicosapentanoic acid ethyl ester; EPA-Vascepa; Ethyl eicosapentaenoate; Ethyl eicosopentaenoate; Ethyl icopenate; Ethyl-EPA; Icosapent ethyl - Amarin Corporation; Icosapentaenoic acid ethyl ester; LAX-101; LAX-101c; Miraxion™; Ultra-pure eicosapentaenoic acid; Ultra-pure EPA; Ultra-pure ethyl ecosapentaenoic acid; Ultra-pure ethyl EPA; Vascepa; VAZKEPA; Vazkepa

Latest Information Update: 09 Apr 2024

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At a glance

  • Originator Scarista
  • Developer Amarin Corporation; Biologix FZCo; Eddingpharm; HLS Therapeutics; University of Leeds; Yorkshire Cancer Research
  • Class Antidementias; Antidepressants; Antihyperlipidaemics; Antineoplastics; Antiplatelets; Antivirals; Eicosanoids; Esters; Omega 3 fatty acids; Reactive oxygen species; Small molecules; Vascular disorder therapies
  • Mechanism of Action Diacylglycerol O acyltransferase inhibitors; Phospholipase A2 inhibitors; Platelet aggregation inhibitors; Triglyceride modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Huntington's disease
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Marketed Hypertriglyceridaemia
  • Registered Cardiovascular disorders
  • Phase III Colorectal cancer; COVID 2019 infections; Liver metastases
  • Discontinued Huntington's disease; Major depressive disorder; Memory disorders; Parkinson's disease; Psychotic disorders

Most Recent Events

  • 03 Apr 2024 Amarin has patent pending from the 2033 patent family for ethyl eicosapentaenoic acid in Europe
  • 03 Apr 2024 Amarin has patent protection for ethyl eicosapentaenoic acid in Europe
  • 25 Mar 2024 Launched for Hypertriglyceridaemia in China (PO) prior to March 2024
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