Research programme - 5T4 monoclonal antibody conjugates - Oxford BioMedica/Pfizer

Drug Profile

Research programme - 5T4 monoclonal antibody conjugates - Oxford BioMedica/Pfizer

Alternative Names: 5T4 MAb-toxin; Anti-5T4 antibody; CME-548; OBA1-H8

Latest Information Update: 06 Sep 2013

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At a glance

  • Originator Oxford BioMedica
  • Developer Pfizer
  • Class Aminoglycosides; Antineoplastics; Drug conjugates; Enediynes; Immunotoxins; Monoclonal antibodies
  • Mechanism of Action Apoptosis stimulants; Immunomodulators; Membrane glycoprotein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Cancer

Most Recent Events

  • 06 Sep 2013 Preclinical development in Cancer is ongoing in USA
  • 04 May 2011 Oxford BioMedica broadens 5T4 antibody collaboration with Pfizer; Pfizer granted non-exclusive rights for the diagnostic use of 5T4 antibodies in an amendment to an existing licensing agreement
  • 05 Apr 2011 Monoclonal antibody OBA1-H8 is still in preclinical trials for Cancer in USA
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