Drug Profile


Alternative Names: B-1939; B-1939 mesylate; E 7386; E-7389; ER-086526; Eribrin; Eribulin mesylate; Halaven; NSC-707389

Latest Information Update: 24 May 2017

Price : $50

At a glance

  • Originator Eisai Co Ltd; Harvard University
  • Developer Asan Medical Center; Eisai Co Ltd; Emory University; Merck & Co; National Cancer Institute (USA); PIQUR Therapeutics
  • Class 2 ring heterocyclic compounds; Antineoplastics; Cyclic ethers; Furans; Ketones; Macrocyclic compounds; Small molecules
  • Mechanism of Action Apoptosis stimulants; Cadherin modulators; Receptor protein-tyrosine kinase modulators; Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Soft tissue sarcoma
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Breast cancer; Soft tissue sarcoma
  • Phase III Non-small cell lung cancer
  • Phase I/II Bladder cancer
  • Phase I Cancer; Solid tumours
  • Discontinued Prostate cancer

Most Recent Events

  • 27 Feb 2017 Launched for Breast cancer (Late-stage disease, Metastatic disease, Second-line therapy or greater) in South Africa (IV)
  • 11 Dec 2016 Interim efficacy and adverse events data from a phase I/II trial in Breast cancer (Combination therapy, Metastatic disease, Second-line therapy or greater) released by Eisai (9208776; 9208772)
  • 01 Dec 2016 Registered for Breast cancer (Metastatic disease, Second-line therapy or greater) in South Africa (IV)
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