Drug Profile


Alternative Names: MK-5348; SCH 530348; TRA-SCH 530348; Zontivity

Latest Information Update: 25 Mar 2017

Price : $50

At a glance

  • Originator Schering-Plough
  • Developer Duke Clinical Research Institute; Kirby Institute for infection and immunity in society; Merck & Co
  • Class 3-ring heterocyclic compounds; Antithrombotics; Carbamates; Cardiovascular therapies; Lactones; Pyridines
  • Mechanism of Action PAR 1 receptor antagonists; Thrombin receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Arterial thrombosis
  • Phase I/II Blood coagulation disorders; Inflammation
  • No development reported Cerebral infarction

Most Recent Events

  • 13 Mar 2017 Aralez plans to re-launch vorapaxar in USA in June 2017
  • 07 Sep 2016 Vorapaxar licensed to Aralez Pharmaceuticals in USA and Canada
  • 10 Jun 2016 Medical University of Vienna initiates enrolment in a phase II trial for Coagulation disorders (In Volunteers) (PO) in Austria (EudraCT2016-000309-34)
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