Drug Profile


Alternative Names: CF-101; IB-MECA; SI-615

Latest Information Update: 29 Nov 2016

Price : $50

At a glance

  • Originator Can-Fite BioPharma
  • Developer Can-Fite BioPharma; OphthaliX
  • Class Amides; Anti-inflammatories; Antiepileptic drugs; Antineoplastics; Antirheumatics; Iodobenzenes; Neuroprotectants; Purine nucleosides; Ribonucleosides; Small molecules
  • Mechanism of Action Adenosine A3 receptor agonists; Apoptosis inhibitors; Immunosuppressants; Interleukin 17 receptor antagonists; Interleukin-23 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II/III Psoriasis
  • Phase II Glaucoma; Rheumatoid arthritis
  • Phase I Uveitis
  • Preclinical Osteoarthritis
  • Discontinued Colorectal cancer; Dry eyes; Solid tumours

Most Recent Events

  • 07 Apr 2017 Can-Fite plans the phase III ACRobat trial for Rheumatoid arthritis in the USA, Europe, Canada and Israel (NCT02647762)
  • 25 Nov 2016 Can-Fite receives patent allowance from European Patent Office for A3 Adenosine Receptor Agonist Piclidenoson (IB-MECA/CF-101) for treatment of Psoriasis
  • 01 Nov 2016 Can-Fite reaches agreement with EMA regarding protocol design and registration plan for use in Psoriasis
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