Research programme: liver X receptor modulators - Bristol-Myers Squibb/Exelixis

Drug Profile

Research programme: liver X receptor modulators - Bristol-Myers Squibb/Exelixis

Alternative Names: EXEL 2255; LXR modulators

Latest Information Update: 20 Oct 2015

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At a glance

  • Originator Exelixis
  • Developer Bristol-Myers Squibb; Exelixis
  • Class Small molecules
  • Mechanism of Action Liver X receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Atherosclerosis; Hypercholesterolaemia

Most Recent Events

  • 13 Oct 2010 Bristol-Myers Squibb and Exelixis make undisclosed minor amendments to their LXR agreement
  • 10 Nov 2008 Exelixis and Bristol-Myers Squibb extend their research collaboration until January 2010
  • 29 Nov 2007 An IND (or equivalent) has been accepted for a lead compound from this programme
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