Beperminogene perplasmid

Drug Profile

Beperminogene perplasmid

Alternative Names: AMG 0001 01; AMG-0001; Collategene; Hepatocyte growth factor gene therapy - AnGes MG; HGF Plasmid

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator AnGes MG
  • Developer AnGes MG; Osaka University Hospital
  • Class Antiparkinsonians; Gene therapies; Ischaemic heart disorder therapies; Vascular disorder therapies
  • Mechanism of Action Angiogenesis inducing agents; Hepatocyte growth factor stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No
  • Available For Licensing Yes - Ischaemic heart disorders; Lymphoedema; Parkinson's disease

Highest Development Phases

  • Phase III Peripheral arterial disorders
  • Phase I/II Lymphoedema
  • Phase I Arteriosclerosis obliterans; Ischaemic heart disorders; Thromboangiitis obliterans
  • Preclinical Parkinson's disease

Most Recent Events

  • 23 Nov 2016 AnGes plans a long-term follow-up observational clinical trial for Peripheral arterial disorders (in patients with critical limb ischaemia) in USA (IM) (NCT02974179)
  • 27 Jul 2016 Osaka University Hospital terminates phase-I trial in Ischaemic heart disorders in Japan (IM) (UMIN000012942)
  • 20 Jun 2016 AnGes terminates phase III trial in Peripheral arterial disorders in USA, Belgium, Canada, Denmark, Finland, France, Hungary, Italy, Netherlands, Poland and Sweden due to amendment in global development strategy (9198317; NCT02144610)
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