Drug Profile


Alternative Names: Antigen-presenting autologous dendritic cells - Asterias Biotherapeutics; AST-VAC1; Cancer vaccine - Argos/Geron; GRNVAC 1; hTERT RNA vaccine - Argos/Geron; RNA-loaded autologous dendritic cell vaccine - Argos/Geron; VAC1

Latest Information Update: 12 Apr 2017

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At a glance

  • Originator Argos Therapeutics Inc; Geron Corporation
  • Developer Asterias Biotherapeutics
  • Class Cancer vaccines; Dendritic cell vaccines
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase II Acute myeloid leukaemia
  • Discontinued Malignant melanoma; Prostate cancer

Most Recent Events

  • 28 Mar 2017 Asterias Biotherapeutics has patent protection for VAC 1 in South Korea, Israel, Singapore and other jurisdictions (Asterias Biotherapeutics form 10-k, March 2017)
  • 04 Oct 2016 Immunomic Therapeutics in-licenses NTC’s RNA-OUT™ and HyperGro™ technology from Nature Technology Corporation
  • 27 Sep 2016 Asterias Biotherapeutics plans a confirmatory phase IIb trial for VAC 1 in 2018
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