Research programme: integrin antagonists - sigma-tau

Drug Profile

Research programme: integrin antagonists - sigma-tau

Alternative Names: ST-1646

Latest Information Update: 29 Sep 2010

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At a glance

  • Originator Ronzoni Institute for Chemical and Biochemical Research; sigma-tau SpA; University of Bari; University of Milan
  • Class Cyclic peptides
  • Mechanism of Action Angiogenesis inhibitors; Integrin alphaVbeta3 antagonists; Integrin alphaVbeta5 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Solid tumours

Most Recent Events

  • 12 Sep 2006 A preclinical study has been added to the Cancer pharmacodynamics section
  • 14 Feb 2002 A preclinical study has been added to the Cancer pharmacodynamcis section
  • 20 Sep 2001 Preclinical development for Solid tumours in Italy (unspecified route)
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