Research programme: vanilloid receptor antagonists - Ligand/Merck

Drug Profile

Research programme: vanilloid receptor antagonists - Ligand/Merck

Alternative Names: NGD 8695; NRGN-16

Latest Information Update: 04 Nov 2017

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At a glance

  • Originator Merck & Co; Neurogen Corporation
  • Class Pyridazines; Small molecules
  • Mechanism of Action TRPV cation channel antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • No development reported Pain; Urinary incontinence

Most Recent Events

  • 04 Nov 2017 No recent reports of development identified for preclinical development in Pain in USA (PO)
  • 23 Dec 2009 Preclinical development is ongoing in USA
  • 08 Dec 2003 Neurogen and Merck & Co. have formed a research collaboration and combined their vanilloid receptor antagonist programmes
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