Drug Profile


Alternative Names: DJ-927

Latest Information Update: 04 Mar 2015

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At a glance

  • Originator Daiichi Pharmaceutical
  • Developer Genta (CEASED)
  • Class Antineoplastics; Small molecules; Taxanes
  • Mechanism of Action Apoptosis stimulants; Mitosis inhibitors; Tubulin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Gastric cancer; Malignant melanoma
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Bladder cancer; Breast cancer; Colorectal cancer; Gastric cancer; Malignant melanoma; Prostate cancer; Solid tumours

Most Recent Events

  • 15 Dec 2016 Biomarkers information updated
  • 01 Oct 2014 M.D Anderson Cancer Center in collaboration with Genta Incorporated terminates a phase II trial in Malignant melanoma (Second-line therapy or greater) in USA (NCT01064713)
  • 15 Jul 2012 Genta completes enrolment in its phase II trial for Malignant melanoma (second-line therapy) in US (NCT01064713)
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