AD 4

Drug Profile

AD 4

Alternative Names: L-2-Acetamido-3-mercaptopropionamide; N-Acetylcysteinamide; N-Acetylcysteine amide; AD-4; NACA

Latest Information Update: 24 Jan 2015

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At a glance

  • Originator Hebrew University of Jerusalem
  • Developer Eucalyptus Ltd; Yissum Research Development Company
  • Class Eye disorder therapies; Neuroprotectants; Small molecules; Sulfhydryl compounds
  • Mechanism of Action Antioxidants; Chelating agents; Free radical scavengers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Neurodegenerative disorders

Most Recent Events

  • 09 Jan 2008 Preclinical trials in Neurodegenerative disorders in USA (PO)
  • 09 Jan 2008 AD 4 exclusively licensed to Eucalyptus Ltd. worldwide for the treatment of Neurodegenerative disorders
  • 24 Apr 2007 No development reported - Preclinical for Neuroprotection in Israel (PO)
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