Drug Profile


Alternative Names: Alzheimer's disease virus-like particle-based vaccine - Novartis; Alzheimer's disease VLP-based vaccine - Novartis; Beta-amyloid protein immunotherapy - Novartis; CAD 106; Immunodrug™ for Alzheimer's disease - Novartis

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Cytos Biotechnology
  • Developer Cytos Biotechnology; Novartis
  • Class Alzheimer vaccines; Antidementias; Neuroprotectants; Virus-like particle vaccines
  • Mechanism of Action Amyloid beta-protein inhibitors; Immunomodulators; Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II/III Alzheimer's disease
  • Discontinued Hypersensitivity; Rheumatoid arthritis

Most Recent Events

  • 15 Feb 2017 Discontinued - Phase-II for Alzheimer's disease in European Union, USA, Switzerland (SC)
  • 13 Jun 2016 Phase-II/III clinical trials in Alzheimer's disease in Belgium and Finland (IM) (EudraCT2015-002715-15)
  • 22 Dec 2015 Phase-II/III clinical trials in Alzheimer's disease in USA (IM) (NCT02565511)
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