Drug Profile


Alternative Names: ASP-9766; BAL-8557; BAL-8557-000; BAL-8557-002; BAL-9557; Cresemba; Isavuconazonium chloride; Isavuconazonium sulfate; Isavuconazonium sulphate

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Basilea Pharmaceutica
  • Developer Astellas Pharma; Basilea Pharmaceutica
  • Class Antifungals; Nitriles; Pyridines; Small molecules; Triazoles
  • Mechanism of Action 14-alpha demethylase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Candidiasis; Aspergillosis; Candidaemia; Zygomycosis
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Marketed Aspergillosis; Zygomycosis
  • Phase III Candidiasis
  • Discontinued Mycoses

Most Recent Events

  • 09 Aug 2017 Astellas Pharma plans a phase I trial for Haematological malignancies (NCT03241550)
  • 14 Jun 2017 Isavuconazonium licensed to Avir Pharma for commercialisation in Canada
  • 14 Jun 2017 Isavuconazonium licensed to Pfizer for commercialisation in Europe (excluding Nordic countries), Russia, Turkey and Israel
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