Drug Profile


Alternative Names: Epivir/ziagen; EPZICOM; Kivexa; lamivudine/abacavir; Ziagen/Epivir

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator GlaxoSmithKline; ViiV Healthcare
  • Developer GlaxoSmithKline; Mylan
  • Class Antiretrovirals; Cyclopentanes; Cyclopropanes; Dideoxynucleosides; Pyrimidine nucleosides; Small molecules
  • Mechanism of Action HIV replication inhibitors; Nucleoside reverse transcriptase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Marketed HIV infections

Most Recent Events

  • 15 Dec 2016 Biomarkers information updated
  • 05 Aug 2011 ViiV healthcare files lawsuit against Teva Pharmaceutical for infringing patent US 6 417 191
  • 01 Jul 2010 GlaxoSmithKline completes a phase III trial (NCT00440947, ARIES) of a regimen of atazanavir + ritonavir in combination with abacavir/lamivudine in treatment-naive patients with HIV-1 infection in USA, Canada, and Puerto Rico
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