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Saxagliptin - AstraZeneca

Drug Profile

Saxagliptin - AstraZeneca

Alternative Names: BMS-477118; Onglyza; OPC-262

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator Bristol-Myers Squibb
  • Developer AstraZeneca; Bristol-Myers Squibb; Otsuka Pharmaceutical
  • Class Adamantanes; Antihyperglycaemics; Azabicyclo compounds; Dipeptides; Nitriles; Organic bridged compounds; Piperidines; Small molecules
  • Mechanism of Action Dipeptidyl peptidase 4 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Type 2 diabetes mellitus

Most Recent Events

  • 08 Mar 2022 Saxagliptin is still in phase III trials for Type 2 diabetes mellitus (Adjunctive treatment, In adolescents, In children) in USA, Australia, Argentina, United Kingdom, Ukraine, Turkey, Thailand, Taiwan, Russia, Romania, Philippines, New Zealand, Mexico, Malaysia, South Korea, Italy, Israel, India, Colombia, Chile, Brazil, Canada, Finland, Poland (PO) (NCT03199053)
  • 13 Nov 2020 Efficacy results from a phase III trial for Type 2 diabetes mellitus presented at 70th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD-2020)
  • 29 Jan 2020 Saxagliptin is still in phase III trials for Type 2 diabetes mellitus (Adjunctive treatment, In adolescents, In children) in USA, Australia, Argentina, United Kingdom, Ukraine, Turkey, Thailand, Taiwan, Russia, Romania, Philippines, New Zealand, Mexico, Malaysia, South Korea, Italy, Israel, India, Colombia, Chile, Brazil, Canada, Finland, Poland (PO) (NCT03199053)
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