Estradiol/nomegestrol monophasic

Drug Profile

Estradiol/nomegestrol monophasic

Alternative Names: E2-Nomac monophasic; E2/Nomac monophasic; EMM-310066; IOA; MK-8175A; NOMAC-E2; Nomac-E2 monophasic; NOMAC/E2; Nomac/E2 monophasic; Nomegestrol acetate/17 beta-estradiol; Nomegestrol acetate/estradiol; Nomegestrol/estradiol; Org 10486-0/Org 2317; SCH 900121; Zoely

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Theramex SAM
  • Developer Merck & Co
  • Class Estradiol congeners; Estrenes; Hormonal contraceptives; Hormonal replacements; Pregnadienes; Progesterone congeners; Small molecules
  • Mechanism of Action Estrogen receptor agonists; Progesterone receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Marketed Pregnancy

Most Recent Events

  • 15 Dec 2016 Biomarkers information updated
  • 03 Dec 2014 Merck terminates phase III trial in Contraception/Pregnancy (Prevention) in USA (NCT01656434)
  • 10 Feb 2014 Teva Pharmaceutical Industries has patent protection for estradiol/nomegestrol monophasic in Europe
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