IRX 5183

Drug Profile

IRX 5183

Alternative Names: AGN 195183; NRX 195183; VTP 195183

Latest Information Update: 14 May 2016

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At a glance

  • Originator Allergan
  • Developer Io Therapeutics
  • Class Antineoplastics; Antipsoriatics
  • Mechanism of Action Retinoic acid receptor alpha agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Cancer
  • No development reported Psoriasis
  • Discontinued Stem cell mobilisation

Most Recent Events

  • 14 May 2016 Phase-I/II development for Cancer is ongoing in USA (PO)
  • 22 Apr 2016 Sidney Kimmel Comprehensive Cancer Center plans a phase I/II trial for Acute myeloid leukaemia, Myelodysplastic syndrome and Chronic myelomonocytic leukaemia (Second-line therapy or greater) in USA (PO) (NCT02749708)
  • 06 Oct 2011 Clinical trials in Psoriasis in USA (PO)
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